MindMap Gallery Physiology blood circulation 2
The mind map of Physiology and Blood Circulation 2 shares the knowledge of vascular physiology and the regulation of cardiovascular activities (neuroregulation, humoral regulation, autoregulation, and long-term regulation of arterial blood pressure). Everyone is welcome to learn.
Edited at 2023-06-18 20:36:10El cáncer de pulmón es un tumor maligno que se origina en la mucosa bronquial o las glándulas de los pulmones. Es uno de los tumores malignos con mayor morbilidad y mortalidad y mayor amenaza para la salud y la vida humana.
La diabetes es una enfermedad crónica con hiperglucemia como signo principal. Es causada principalmente por una disminución en la secreción de insulina causada por una disfunción de las células de los islotes pancreáticos, o porque el cuerpo es insensible a la acción de la insulina (es decir, resistencia a la insulina), o ambas cosas. la glucosa en la sangre es ineficaz para ser utilizada y almacenada.
El sistema digestivo es uno de los nueve sistemas principales del cuerpo humano y es el principal responsable de la ingesta, digestión, absorción y excreción de los alimentos. Consta de dos partes principales: el tracto digestivo y las glándulas digestivas.
El cáncer de pulmón es un tumor maligno que se origina en la mucosa bronquial o las glándulas de los pulmones. Es uno de los tumores malignos con mayor morbilidad y mortalidad y mayor amenaza para la salud y la vida humana.
La diabetes es una enfermedad crónica con hiperglucemia como signo principal. Es causada principalmente por una disminución en la secreción de insulina causada por una disfunción de las células de los islotes pancreáticos, o porque el cuerpo es insensible a la acción de la insulina (es decir, resistencia a la insulina), o ambas cosas. la glucosa en la sangre es ineficaz para ser utilizada y almacenada.
El sistema digestivo es uno de los nueve sistemas principales del cuerpo humano y es el principal responsable de la ingesta, digestión, absorción y excreción de los alimentos. Consta de dos partes principales: el tracto digestivo y las glándulas digestivas.
blood circulation
Vascular Physiology
Functional characteristics of various types of blood vessels
Classified by functionality
Elastic reservoir blood vessels: the main trunk of the aorta, pulmonary artery and their largest branches; it converts the intermittent ejection of blood from the ventricles into the continuous flow of blood in the blood vessels, and at the same time reduces the fluctuation amplitude of blood pressure during the cardiac cycle.
Distribution blood vessels: middle arteries; transports blood to various organs and tissues
Precapillary resistance vessels: arterioles and arterioles; their systolic and systolic activities change the blood volume and caliber, thereby changing the resistance to blood flow and the blood flow of the organs and tissues where they are located.
Precapillary sphincter: Smooth muscle surrounding the origin of true capillaries; controls the opening or closing of capillaries
Exchange vessels: true capillaries, composed only of a single layer of endothelial cells; the main site for material exchange
Postcapillary resistance vessels: refers to venules; changes capillary blood pressure, blood volume and filtration, affecting the distribution of body fluids inside and outside blood vessels.
Capacitive vessels: the venous system; serves as a reservoir for blood
Short-circuiting vessel: a direct anastomosis between arterioles and venules in a vascular bed; involved in thermoregulation
endocrine function of blood vessels
Endothelial cells: vasodilator active substances are NO, hydrogen sulfide, and prostacyclin; vasoconstrictor active substances are endothelin and TXA2
Smooth muscle cells: regulate the tone and blood flow of local blood vessels
Other cells: protect, support and nourish blood vessels
Hemodynamics
arterial blood pressure
forming conditions
The cardiovascular system is adequately filled with blood
heart ejection
peripheral resistance
Elastic reservoir function of aorta and great arteries
Pulse pressure = systolic blood pressure - diastolic blood pressure; mean arterial pressure = diastolic blood pressure 1/3 pulse pressure
Factors affecting arterial blood pressure
Cardiac stroke volume: mainly affects systolic blood pressure
Heart rate: mainly affects diastolic blood pressure
Peripheral resistance: mainly affects diastolic blood pressure
Elastic reservoir function of aorta and large arteries
Matching of circulating blood volume and vascular system capacity
Venous blood pressure and venous blood return volume
Classification
Central venous pressure: blood pressure in the right atrium and large veins in the chest; the stronger the heart's ejection capacity/the slower the venous return rate, the lower the central venous pressure
Peripheral venous pressure: blood pressure in the veins of various organs
venous blood return volume
Venous blood return volume = (peripheral venous pressure - hydrostatic pressure) / venous blood flow resistance
Influencing factors
mean systemic filling pressure
myocardial contractility
skeletal muscle compression
Postural changes
respiratory movements
Microcirculation
As a place where the body exchanges substances and gases with the external environment, it plays an important role in maintaining the metabolism of tissue cells and the homeostasis of the internal environment.
Blood circulation between arterioles and venules; including arterioles (general gate), posterior arterioles, precapillary sphincter (branch gates), true capillaries, blood-operating capillaries, arteriovenous anastomosis branches and venules ( rear gate) etc.
Blood flow pathways: circuitous pathways, direct pathways and arteriovenous short circuits
tissue fluid
The force of capillary blood pressure and interstitial fluid colloid osmotic pressure to promote fluid filtration from the inside to the outside of capillaries, the force of interstitial fluid hydrostatic pressure and plasma colloid osmotic pressure of outward to inward reabsorption; effective filtration pressure = (capillary blood pressure, interstitial fluid colloid osmotic pressure) - (Tissue fluid hydrostatic pressure, plasma colloid osmotic pressure)
Factors affecting tissue fluid production
Capillary effective hydrostatic pressure: capillary blood pressure - tissue fluid hydrostatic pressure "increases edema"
Effective colloid osmotic pressure: plasma-tissue fluid colloid osmotic pressure "reduces edema"
capillary wall permeability
lymphatic drainage
Lymph production and return
Auxiliary system for the return of tissue fluid to blood
Recycle proteins and absorb nutrients; remove red blood cells, bacteria, and foreign matter from tissues; balance the production and absorption of tissue fluid
Regulation of cardiovascular activity
neuromodulation
cardiovascular innervation
Sympathetic nerve-NE-β1 receptor ( )
Vagus nerve-ACh-M receptor (-)
innervation of blood vessels
Vasoconstrictor nerve fibers: sympathetic vasoconstrictor nerves
Vasodilator nerve fibers: sympathetic vasodilator nerve fibers, parasympathetic vasodilator nerve fibers, spinal dorsal root vasodilator fibers, peptide vasodilator nerve fibers
cardiovascular center
Spinal cord, medulla oblongata, hypothalamus, other
cardiovascular reflex
Carotid sinus and aortic arch baroreflex (hypertensive response)
Carotid and aortic body chemoreceptive reflexes: regulate respiration, thereby affecting RP
Cardiovascular reflexes caused by cardiopulmonary receptors: regulate circulating blood volume and extracellular fluid volume
body fluid regulation
renin-angiotensin system
Renin is an acid protease synthesized and secreted by juxtaglomerular cells
The function of Ang II is vasoconstriction, increased release of transmitters from sympathetic nerves, increased central nervousness of sympathetic vasoconstrictors, and increased aldosterone production.
Factors that stimulate renin secretion: reduced resting potential; reduced circulating blood volume; enhanced sympathetic nerve excitation
Adrenaline and norepinephrine
Vasopressin VP "Antidiuretic hormone ADH"
Synthesized by neurons in the supraoptic and paraventricular nuclei of the hypothalamus, stored and released by the neurohypophysis
Antidiuretic effect occurs under physiological conditions; when the concentration increases significantly, vasoconstriction causes an increase in blood pressure
Maintain constant extracellular fluid volume and arterial blood pressure
Increased ADH production: increased plasma crystal osmotic pressure; decreased blood volume and resting potential; pain, excitement, and hypoxia
Vasoactive substances produced by vascular endothelium
Kallikrein-kinin system
Cardiovascular active peptide ANP (reduces renal tubular reabsorption capacity)
self-regulation
Metabolic autoregulatory mechanisms
myogenic autoregulatory mechanisms
Long-term regulation of arterial blood pressure
Short-term adjustment: through neuromodulation, adjust myocardial contractility and vascular peripheral resistance through various cardiovascular reflexes
Long-term regulation: achieved through renal regulation of extracellular fluid volume
Influencing factors: vasopressin VP; atrial natriuretic peptide ANP; RAS system, aldosterone; sympathetic nervous system activity