MindMap Gallery Biology mind map
A mind map about organisms, including the evolution and diversity of organisms, classification and identification of microorganisms, etc. Hope this helps!
Edited at 2023-11-21 23:16:15El cáncer de pulmón es un tumor maligno que se origina en la mucosa bronquial o las glándulas de los pulmones. Es uno de los tumores malignos con mayor morbilidad y mortalidad y mayor amenaza para la salud y la vida humana.
La diabetes es una enfermedad crónica con hiperglucemia como signo principal. Es causada principalmente por una disminución en la secreción de insulina causada por una disfunción de las células de los islotes pancreáticos, o porque el cuerpo es insensible a la acción de la insulina (es decir, resistencia a la insulina), o ambas cosas. la glucosa en la sangre es ineficaz para ser utilizada y almacenada.
El sistema digestivo es uno de los nueve sistemas principales del cuerpo humano y es el principal responsable de la ingesta, digestión, absorción y excreción de los alimentos. Consta de dos partes principales: el tracto digestivo y las glándulas digestivas.
El cáncer de pulmón es un tumor maligno que se origina en la mucosa bronquial o las glándulas de los pulmones. Es uno de los tumores malignos con mayor morbilidad y mortalidad y mayor amenaza para la salud y la vida humana.
La diabetes es una enfermedad crónica con hiperglucemia como signo principal. Es causada principalmente por una disminución en la secreción de insulina causada por una disfunción de las células de los islotes pancreáticos, o porque el cuerpo es insensible a la acción de la insulina (es decir, resistencia a la insulina), o ambas cosas. la glucosa en la sangre es ineficaz para ser utilizada y almacenada.
El sistema digestivo es uno de los nueve sistemas principales del cuerpo humano y es el principal responsable de la ingesta, digestión, absorción y excreción de los alimentos. Consta de dos partes principales: el tracto digestivo y las glándulas digestivas.
microbial system evolution, Classification and Ecology
biological evolution and its diversity
Primitive life forms and their evolution
primitive life form
Primitive atmosphere → small organic molecules → large organic molecules → primitive ocean → primitive life
evolution of life
Simple organic molecules such as amino acids and nucleic acids→Prokaryotes→Eukaryotes
The scale molecule of biological evolution
Five Realms Theory
Proposed by Robert. H. Whittaker, living things include the kingdoms Animalia, Plantarum, Fungi, Protists, and Prokaryotes
16S rRNA is the most suitable scale to describe the evolution of biological systems
reason
① The function of rRNA in various organisms is to participate in protein synthesis, and this function has remained unchanged
②The 16S rRNA molecule has both highly conserved regions, appropriate moderately conserved regions, and highly variable regions, which is suitable for the study of various biological relationships without evolutionary distance.
③16S rRNA has a suitable molecular weight and is convenient for sequence analysis
④16S rRNA is commonly found in prokaryotes and eukaryotes and can be used as a measure of the evolution of various organisms.
phylogenetic tree
definition
In the study of biological evolution and systematic classification, a tree-like branch diagram is often used to summarize the genetic relationships between various (types of) organisms. This tree-like branch diagram is called a phylogenetic tree. Phylogenetic trees constructed by comparing the numerical differences between biological macromolecule sequences are collectively called molecular phylogenetic trees.
In 1981, Woese first proposed a phylogenetic tree covering the entire world of life (the knot at the root of the phylogenetic tree represents the first life on earth, the common ancestor of living things. It is divided into three evolutionary routes, forming three original kingdoms: ① Archaea ②Primary Kingdom of Eubacteria ③Primary Kingdom of Eukaryotes
Archaea (tertiary organisms)
unique traits
①Special cell membrane lipids
②The composition of the cell wall is unique and diverse
③The 16S rRNA of the ribosome has a unique nucleotide sequence, which is different from both eubacteria and eukaryotes
④ The nucleotide sequence of tRNA is unique and does not contain thymine
⑤The starting code for protein synthesis is methionine, which is the same as that of eukaryotes
⑥ Unique sensitivity to antibiotics
⑦ Its ecological environment is unique
Microbial classification and identification
Microbial taxa and classes
1. species
It is the most basic classification unit. It can be defined as a collection of similar strains, which should be significantly different from strains of other groups in terms of performance characteristics, genetic relationships, etc.
2. subspecies or variety
A pure species of a microorganism isolated from nature must completely match the recorded characteristics of a known typical species in order to be identified as the same species. Sometimes, most of the characteristics of the isolated pure species are completely consistent with the typical species, but there is a certain characteristic that is different from the typical species, and this characteristic is stable and will not differentiate it into a new species, the microorganism is called Subspecies or variant of a typical bacterial species.
3. Type (type and form)
When the character differences between different strains of the same species and the same subspecies are not enough to distinguish them as new subspecies, they can be divided into different types.
4. Group or group
In nature, it is often found that some types of microorganisms are between two other microorganisms in terms of characteristics and cannot be strictly distinguished from each other, so they are called the same "group".
5. strain
Refers to the pure culture of the same microorganism from different sources.
Introduction to Bacterial Classification Systems
bacterial classification system
"Identification of Bacteria and Actinomycetes"
Berger's Manual of Identification Bacteriology
"Bacterial Taxonomy"
fungal classification system
Ainsworth system
V.Arx System
Kendrick system
"Fungi Dictionary"
Alexopoulos&Mins System
virus classification system
According to the characteristics of nucleic acid structure
double-stranded DNA virus
single-stranded DNA virus
DNA and RNA retroviruses
double-stranded RNA virus
negative single-stranded RNA virus
Positive single-stranded RNA virus
subviral factors
Depends on the host
Archaeal viruses
algae virus
Bacterial virus
Mycovirus
invertebrate viruses
Mycoplasma virus
plant viruses
vertebrate viruses
Microbial classification and identification technology
Morphological and physiological and biochemical characteristics
form
In terms of cell structure, the presence or absence of motility, the location and number of flagella, the presence or absence of spores, the location and shape of spores, and cell contents can be observed. In the staining reaction, Gram staining and acid-fast staining should be performed to indicate whether the reaction is positive or negative. In terms of colony morphology, it is to observe the characteristics of colonies generated by microorganisms after culturing on agar plates.
Physiology and biochemistry
Physiological and biochemical differences are essentially differences in enzymes and proteins, which indirectly reflect differences in microbial genomes.
Serological testing and phage typing
serology test
The basic principle of serological reaction is to use known bacterial species, types or strains to prepare antiserum, and identify minor differences in unknown bacterial species, types or strains based on whether it has a specific serological reaction with the object to be identified.
Phage typing
Bacteriophages are often highly specific for host infection and lysis, that is, a phage can often only infect and lyse one type of bacteria, or even only a certain strain within a species.
Cell wall composition analysis
It is currently known that the cell wall components of bacteria, molds and yeasts are significantly different, so the cell wall component analysis can be used to classify microorganisms.
Gas chromatography identification
It is generally believed that the chemical structure of each substance has a specific infrared absorption spectrum. If the absorption spectra of two samples are exactly the same, they can be initially It was initially believed that they were the same substance, so people used infrared spectroscopy technology to measure the chemical composition of microbial cells to classify microorganisms.
Nucleic acid analysis and molecular hybridization
DNA is the main carrier of genetic information, and genetic information is determined by the sequence of the four bases on the DNA chain. Different organisms, and the more distantly related the species, the greater the difference in the sequence of their base pairs. . Therefore, taxonomists consider using the characteristics of DNA, the genetic material of prokaryotic animals, as one of the basis for classification, mainly including GC content measurement, nucleic acid hybridization technology and sequence analysis, etc.
numerical taxonomy
The numerical classification method is developed based on the classification principles published by the French botanist Adanson and with the help of modern computer technology.
Differences from traditional classification
①The classification features used in the traditional method are divided into primary and secondary categories. The numerical method is based on the "principle of equal importance", regardless of priority, and is classified into groups by calculating the total similarity value between strains.
② The traditional method uses the bifid method to sort out the experimental results based on a few characteristics and arrange taxa one by one. The numerical method uses more features, usually 50 to 60, and even more than 100 features. Comparing pairs of strains requires a large amount of data processing and requires borrowing. This can only be achieved with the help of a computer.
Zhang Yujie, Class 3 Pharmaceutical Engineering Class 2021 2102010327