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Idiopathic thrombocytopenic purpura
Idiopathic thrombocytopenic purpura mind map, idiopathic thrombocytopenic purpura (ITP) is a clinical syndrome caused by increased platelet destruction due to abnormal immune function, also known as immune thrombocytopenic purpura.
Edited at 2024-10-27 16:41:46- Fortpflanzungssystem
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Idiopathic thrombocytopenic purpura
- Fortpflanzungssystem
Diese Vorlage zeigt die Struktur und Funktion des Fortpflanzungssystems in Form einer Mind Map. Es führt die verschiedenen Komponenten der internen und externen Genitalien ein und sortiert das Wissen eindeutig aus, um Ihnen dabei zu helfen, mit den wichtigsten Wissenspunkten vertraut zu werden.
- Interpretation und Zusammenfassung des Beziehungsfeldes E-Book
Dies ist eine Mind Map über die Interpretation und Zusammenfassung des Beziehungsfeldes E-Book, des Hauptinhalts: Überblick über die Essenzinterpretation und Übersicht über das Feld E-Book. "Relationship Field" bezieht sich auf das komplexe zwischenmenschliche Netzwerk, in dem ein Individuum andere durch spezifische Verhaltensweisen und Einstellungen beeinflusst.
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Idiopathic thrombocytopenic purpura
Cause (cause)
immune factors
Autoantibodies attack platelets. These antibodies are mainly produced in the spleen, and the spleen is also the main organ where platelets are destroyed.
other factors
Virus infection
ITP in children is often related to viral infection, which may be an immune complex disease caused by the immune response after viral infection. Adults can be infected by HIV.
drug factors
rare
Pathology (edge)
increased platelet destruction
More than half of ITP patients have specific autoantibodies in their bodies. The platelets sensitized by the autoantibodies are excessively destroyed by the monocyte-macrophage system, leading to thrombocytopenia.
Decreased platelet production
Autoantibodies damage megakaryocytes or inhibit the release of platelets from megakaryocytes, leading to insufficient platelet production and a series of clinical manifestations.
Clinical manifestations (fruit)
skin bleeding
The main manifestations are bleeding in the skin and mucous membranes, such as petechiae, purpura, ecchymosis, difficulty in stopping bleeding after trauma, bleeding gums, nose bleeding, etc.
Internal bleeding
Although severe visceral bleeding is rare, some patients may suffer from sudden exacerbation of their condition due to infection, etc., resulting in extensive and severe bleeding of the skin and mucous membranes, or even visceral bleeding. Fatal symptoms may also be induced by high fever, emotion, high blood pressure, etc. of intracranial hemorrhage.
anemia
Menorrhagia, caused by chronic bleeding.
Same cause but different effect
immune factors
systemic lupus erythematosus
Both are related to autoimmune reactions. SLE is a multi-system disease affecting multiple organs such as skin, joints, kidneys, etc., while ITP mainly affects the blood system, causing thrombocytopenia.
rheumatoid arthritis
Both involve autoimmune responses that lead to inflammation and tissue damage. RA mainly affects the joints, causing joint inflammation and pain, while ITP mainly affects the blood system, causing bleeding tendencies.
Sjogren's syndrome
Both are associated with autoimmune reactions, with Sjögren's syndrome primarily affecting the glands that produce saliva and tears, causing dry eyes and mouth.
Thyroid disease
An autoimmune reaction may cause thyroid dysfunction, resulting in hyper or hypothyroidism.
viral infection
Aplastic anemia (hepatitis virus)
Aplastic anemia affects all types of cells. Due to a decrease in whole blood cells, patients suffer from anemia symptoms, infections, and bleeding tendencies, while ITP mainly presents with bleeding symptoms.
HIV
HIV is a disease that affects the immune system throughout the body, while ITP mainly affects the blood system
Same effect but different cause
skin bleeding
allergic purpura
It is a disease caused by inflammation of small blood vessels, causing petechiae and petechiae to appear on the skin. It is usually associated with an abnormal immune system response but is not due to an abnormality in platelet function or number.
DIC
DIC is due to the imbalance of the coagulation and anticoagulation systems in the body, which activates the coagulation pathway, leading to the formation of microthrombi, while consuming coagulation factors and platelets, causing bleeding tendencies.
Internal bleeding
hemophilia
Internal bleeding caused by a deficiency of a clotting factor such as hemophilia A (factor VIII deficiency) or hemophilia B (factor IX).
Cirrhosis
The synthesis of coagulation factors caused by liver cirrhosis is reduced, causing internal bleeding.
DIC
DIC may cause multi-organ failure and bleeding, including thrombocytopenia. DIC is due to an imbalance in the systemic coagulation and anticoagulation systems, leading to the formation of microthromboses, while ITP is due to immune-mediated destruction of platelets.
anemia
iron deficiency anemia
Anemia due to insufficient iron intake or blood loss.
hemolytic anemia
Anemia caused by the rapid destruction of red blood cells.
causal loop
increased platelet destruction
Autoimmune reaction ➡️ Increased platelet destruction ➡️ Release of pro-inflammatory factors ➡️ Enhanced autoimmune reaction
Decreased platelet production
Myelosuppression➡️Reduced platelet production➡️Bleeding tendency➡️Further bone marrow suppression➡️Further reduced platelet production