It is caused by the division and proliferation of basal layer cells at the base of the wound, and the differentiation and proliferation of tissue stem cells.

Depends on whether the glandular basement membrane is destroyed

liver regeneration

Completed by sprouting, also known as vascularization

process

Surgical anastomosis is required after separation

The intima can be completely regenerated

The muscle layer is not easy to regenerate and often scar repair (connective tissue connection)

The muscle membrane can be completely regenerated if it continues, otherwise the scar at the separation point will be repaired

Only scar repair

In good condition, it can be completely repaired

Amputation or the severed end is too far and cannot be connected, resulting in traumatic neuroma and intractable pain.

Some of these cells contain myofilaments and are similar to SMC, and are called myofibroblasts.

Early neutrophils, mainly macrophages after 3 days

Interstitial water absorption gradually decreases

Inflammatory cells decrease and disappear

Most of the capillaries disappeared, and a few were transformed into small arteries and veins.

Fibroblasts produce collagen fibers, become fibroblasts, and undergo hyaline degeneration

Keep organs intact

Keeps organs strong (more resistant to tension than granulation tissue)

scar shrinkage

scarring adhesions

Excessive scar tissue proliferation

Local redness and swelling, exudate forming scab

Can reduce wounds

It is caused by the traction of myofibroblasts around the wound

Provide nutrients and growth factors for epithelial regeneration

Not too serious, easy to heal

Peak tensile strength is 90 days

Excessive necrotic tissue, infection, local degeneration and necrosis, inflammatory reaction

The wound is large, the wound shrinks significantly, and more granulation tissue grows

Healing takes longer and scars are larger