MindMap Gallery cardiovascular drugs
This is a mind map about cardiovascular drugs, including diuretics and dehydrating drugs, antihypertensive drugs, antiangina drugs, etc.
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This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
cardiovascular drugs
Diuretics and dehydration medications
Classification
Potent
Furosemide, bumetanide
Thick segment of ascending branch of medullary loop
Medium effect
Hydrochlorothiazide, indapamide
proximal segment of distal convoluted tubule
Antihypertensive
Inefficient
Spironolactone, triamterene, amiloride
distal tubule terminal and collecting duct
Acetazolamide
proximal tubule
anti-angina pectoris
Efficient
Furosemide
Characteristics of action: Rapid, powerful, short-lived, expelling large amounts of water and electrolytes
Pharmacological effects
diuresis
Vasodilatory effect
Clinical application
acute pulmonary edema and cerebral edema
Treat heart failure
First choice
Eliminate all kinds of severe edema
acute and chronic renal failure
Hypercalcemia, adjunctive treatment of hypervascular crisis
acute drug poisoning
Adverse reactions
Water and electrolyte imbalance
Ototoxicity
hyperuricemia
bumetanide
The most powerful diuretic
Medium effect
Hydrochlorothiazide
Pharmacological effects
diuresis
Antihypertensive effect
antidiuretic effect
Clinical application
Edema due to various causes
First choice for mild to moderate cardiac edema
hypertension
diabetes insipidus
Idiopathic hypercalciuria accompanied by kidney stones
Adverse reactions
electrolyte imbalance
High blood Ca2
Metabolic disorders
Increase blood sugar, increase lipids, increase uric acid
Use with caution in patients with gout, diabetes, and hyperlipidemia
Inefficient
potassium sparing diuretics
Aldosterone receptor antagonist: spironolactone
Mechanism
Competitive inhibition of aldosterone receptors
Reduce sodium and conserve potassium
Pharmacological effects
Slow onset, long-lasting, weak efficacy
Clinical application
Refractory edema associated with elevated aldosterone
congestive heart failure
Na channel blockers: triamterene, amiloride
Functional characteristics
Inhibit Na channels
carbonic anhydrase inhibitor
Acetazolamide
Glaucoma and cerebral edema
dehydration medicine
Mannitol
Cerebral edema, glaucoma first choice
Prevent acute renal failure
antihypertensive drugs
diuretics
Hydrochlorothiazide
Hypertension with heart failure, mild
Renin-angiotensin system inhibitors
Angiotensin-converting enzyme inhibitors (ACEIs)
Puli type
Mechanism
Inhibit ACE and reduce AngII production
Slow down the degradation of bradykinin and dilate blood vessels
Clinical application
Applicable to all stages of hypertension
Acute hypertension and diabetes
Captopril
congestive heart failure
captopril, enalapril
Hepatic insufficiency and hypertension in the elderly
fosinapril and benazepril
stable angina pectoris
cilapril
Adverse reactions
hypotension
Hyperkalemia
cough
Teratogenic to fetus
Angiotensin II receptor blockers (ARBs)
Losartan
Mechanism
act on receptors
Inhibit the vasoconstrictor effect of AngII
Functional characteristics
light and short
Suitable for coughs caused by chlorpheniramine
calcium channel blockers
effect
Depress the heart
Protect ischemic myocardium
Reversal of ventricular remodeling
dilate blood vessels
nifedipine
Mechanism
Inhibit Ca2 influx
Features
Fast acting and strong
Ineffective for normal people
Reflexive heart rate caused by long-term use
Clinical application
Treat mild to moderate hypertension
Combined with beta-blockers
Fight increased heart rate
Niqun Diping
nisoldipine
amlodipine
Sympatholytic drugs
central sympatholytic drugs
clonidine
Mechanism
imidazoline receptor agonist
Clinical application
Moderate, ulcerative hypertension and renal hypertension
morphine detoxification drug
open angle glaucoma
Can be used in combination with diuretics
ganglion blocking drugs
mecamylamine, methiophene
adrenergic nerve ending blocking drugs
reserpine
High blood pressure with emotional stress
adrenoceptor blocking drugs
Alpha and beta receptor blockers
labelore
Various types of hypertension accompanied by angina pectoris
Treating Hypertensive Crisis
α1 receptor blockers
Prazosin
Clinical application
mild to moderate hypertension
Moderate hypertension complicated by renal insufficiency
Adverse reactions
The first dose effect is obvious
beta blockers
Non-selective beta-blockers
propranolol
mild to moderate hypertension
People with high blood pressure and angina pectoris
Those with high cardiac output and renin activity and those with cerebrovascular disease
Selective β1 receptor blockers
Metoprolol, atenolol, acebutolol
vasodilators
Hydralazine
dilated arterioles
lower blood pressure
sodium nitroprusside
dilated arterioles
lower blood pressure
dilation of small veins
Decreased cardiac output
Combined use of diuretics and beta-blockers
antianginal drugs
Nitrate lipids
Nitroglycerin
beta blockers
propranolol
calcium channel blockers
nifedipine
Antiplatelet and antithrombotic drugs
anti heart failure drugs
positive inotropes
cardiac glycosides
Long-lasting: Digitoxin
Moderately effective: digoxin
Short-acting: Trichoside K
non-cardiac glycosides
sympathomimetic drugs
Dobutamine
Phosphodiester III inhibitors
Aminrinone
unloading drugs
Renin-angiotensin system inhibitors
beta receptor antagonists
diuretics
vasodilators
antipsychotic drugs
Class I: sodium channel blockers
Class Ia
Quinidine
Procainamide
Class Ib
lidocaine
Phenytoin
Class Ic
propafenone
Class II: beta-adrenoceptor blocking drugs
propranolol
Category III: Drugs that prolong action potential duration
Amiodarone
Class IV: Calcium channel blockers
Verapamil