Wondershare EdrawMind
EdrawMindBiochemistry Lipid Metabolism Mind Map
MindMap Gallery Biochemistry Lipid Metabolism Mind Map
- 35
Biochemistry Lipid Metabolism Mind Map
This is a mind map about biochemistry lipid metabolism, including the composition, function and analysis of lipids, digestion and absorption of lipids, etc.
Edited at 2023-11-18 17:34:31- bacteria
This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
- Plant asexual reproduction
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
- Reproductive development of animals
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
Biochemistry Lipid Metabolism Mind Map
- bacteria
This is a mind map about bacteria, and its main contents include: overview, morphology, types, structure, reproduction, distribution, application, and expansion. The summary is comprehensive and meticulous, suitable as review materials.
- Plant asexual reproduction
This is a mind map about plant asexual reproduction, and its main contents include: concept, spore reproduction, vegetative reproduction, tissue culture, and buds. The summary is comprehensive and meticulous, suitable as review materials.
- Reproductive development of animals
This is a mind map about the reproductive development of animals, and its main contents include: insects, frogs, birds, sexual reproduction, and asexual reproduction. The summary is comprehensive and meticulous, suitable as review materials.
- Recommended to you
- Outline
fat metabolisim
The composition, function and analysis of lipids
Lipids are a wide variety of macromolecular substances with complex structures
Lipids have a variety of complex biological functions
Triglycerides are important energy substances for the body
Fatty acids have many important physiological functions
Provides essential fatty acids
Synthetic unsaturated fatty acid derivatives
Phospholipids are important structural components and signaling molecules
Is an important component of biofilm
Phosphatidylinositol is the precursor of the second messenger
Cholesterol is an important component of biological membranes and the precursor of sterols with important biological functions.
basic structural components of cell membrane
Convert some sterol compounds with important biological functions
Digestion and absorption of lipids
Bile salts assist digestive enzymes in digesting lipids
Absorbed lipids are resynthesized and enter the blood circulation
Triglyceride metabolism
The oxidative decomposition of glycosides produces a large amount of ATP
Start with fat mobilization
Glycerol is converted into glycerol 3-phosphate and used
Beta oxidation is a core step in lipolysis
Activation of fatty acids into fatty acyl-CoA
Fatty acyl-CoA enters mitochondria
Fatty acyl-CoA breaks down acetyl CoA, FADH2, NADH
Dehydrogenation, adding water, dehydrogenation again, thiolysis
ATP calculation
Fatty acids are broken down in the liver to produce ketone bodies
Ketone bodies are produced in the liver
Utilization in extrahepatic tissues
Fatty acids from different sources synthesize triglycerides in different organs through different pathways.
Liver, adipose tissue, and small intestine are the main sites of triglyceride synthesis
Glycerol and fatty acids are the basic raw materials for the synthesis of triglycerides
Two pathways for triglyceride synthesis
Fatty acid activation into fatty acylCOA
Small intestinal mucosal cells synthesize via the monoglyceride pathway
Liver and adipose tissue synthesize via the diacylglycerol pathway
The synthesis of endogenous fatty acids requires the synthesis of palmitic acid
Palmitic acid is synthesized in the cytoplasm
Acetyl COA, ATP, NADPH are the raw materials of palmitic acid
One molecule of palmitic acid is formed by the condensation of one molecule of acetyl COA and seven molecules of malonyl COA.
Palmitate elongation occurs in the endoplasmic reticulum and mitochondria
The endoplasmic reticulum uses malonyl COA as a two-carbon donor
Mitochondria use acetyl COA as a two-carbon donor
The synthesis of unsaturated fatty acids requires the catalysis of multiple desaturases
Fatty acid synthesis is regulated by metabolites and hormones
Raw material supply and acetyl COA
Insulin is the main hormone that regulates
Fatty acid synthase as a target for drug therapy
Phospholipid metabolism
Phosphatidic acid is an important intermediate product in the synthesis of glycerophospholipids
The raw materials for glycerophospholipid synthesis come from sugar, lipid and amino acid metabolism
Two pathways for glycerophospholipid synthesis
Phosphatidylcholine and phosphatidylethanolamine are synthesized via the diglyceride pathway
Inositol phospholipids, serine phospholipids and cardiolipin are synthesized through the CDP-diglycerol pathway
Glycerophospholipids are degraded by phospholipases
Sphingomyelin is an important intermediate product in the synthesis of sphingomyelin
Sphingomyelin is degraded by sphingomyelinase
cholesterol metabolism
Cholesterol comes from food and endogenous synthesis
Main place liver
Acetyl CoA, NADPH are the basic raw materials
A series of reactions using HMG-CoA as the key enzyme
Synthesis is regulated by HMG-CoA reductase
circadian rhythmicity
Allostery, chemical modification, enzyme content regulation
Cholesterol content
meal status
Hormone regulation
Mainly converted into bile acid
Plasma lipoproteins and their metabolism
Blood lipids are the collective name for the lipids contained in plasma
Plasma lipoproteins are the transport and metabolic forms of blood lipids
lipoproteins from different sources
Chylomicrons primarily transport exogenous triglycerides and cholesterol
Very low density protein primarily transports endogenous triglycerides
Low-density protein mainly transports endogenous cholesterol
High-density protein mainly reverses cholesterol transport
Disturbance of plasma lipoprotein metabolism leading to dyslipoproteinemia